I don't want to dump on you all but boy am I getting fustrated. We are STILL working on Kathleen's GI issues. We've been trying to adjust the Amitiza since May without success. The Dr. says sometimes it just takes getting a perfect dose and timing of dosage. In the meantime Kathleen is lucky to get a couple of days of not feeling crappy. Not always pain but just miserable and fustrated. She goes maybe every 5 days by day 3 she's feeling pretty bad. She's missed at elast a day a week of school and comes home early sometimes. I just want her to feel good and be her happy self again. I want this med to work because if it doesn't it will most likely mean surgical intervention. Praying everyday for that little miracle... It just kills me to see her get sooo angry and fustrated and not be able to fix her belly. She actaully said last week her belly isn't working she needs surgery on it. Thanks for listening!