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Thread: Debate on rituximab vs. ocrelizumab (Rituxan vs. Ocrevus) in MS Journal

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    Distinguished Community Member agate's Avatar
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    Default Debate on rituximab vs. ocrelizumab (Rituxan vs. Ocrevus) in MS Journal

    I'm not sure that these articles tell anything not already covered here but just in case anyone is interested, the Multiple Sclerosis Journal has published an article in favor of Rituxan as an acceptable alternative to Ocrevus in treating MS, another article opposed, and a commentary on both articles:

    http://journals.sagepub.com/doi/full...52458518757930 (Yes)

    http://journals.sagepub.com/doi/full...52458518757931 (No)


    http://journals.sagepub.com/doi/full...52458518760717 (Commentary)
    MS diagnosed 1980. Avonex 2002-2005. Copaxone 6/07 - 5/10.
    Member of this MS board since 2001.

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    Distinguished Community Member Sunshine's Avatar
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    These are very interesting articles.

    A nurse at my infusion center said Rituxan is more expensive than Ocrevus. But this article says the opposite.

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    Distinguished Community Member Cherie's Avatar
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    Ocrevus is nearly a third more per dose than rituxan. Made by the same company...Genentech.

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    Distinguished Community Member Sunshine's Avatar
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    Thanks. I guess the RN was misinformed

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    Does it seem like Genentech wants us to take Ocrevus instead of Rituxan? If so, why?

    ANN
    There comes a time when silence is betrayal.- MLK

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    They have put a lot of effort and money into the humanized monoclonal antibody specifically for mS while Rituxan is used in other illnesses and will continue to be used there. I think (don't know for sure) that it is their way of diversifying.

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    Quote Originally Posted by Sunshine View Post
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    These are very interesting articles.

    A nurse at my infusion center said Rituxan is more expensive than Ocrevus. But this article says the opposite.
    This article is correct. Don’t you remember...the patent on rituximab was running out so the company tweaked it, changed the name to Ocrevus, and kept the price high on Ocrevus. Follow the money. It always leads to the truth.
    Linda~~~~

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    Quote Originally Posted by Cherie View Post
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    They have put a lot of effort and money into the humanized monoclonal antibody specifically for mS while Rituxan is used in other illnesses and will continue to be used there. I think (don't know for sure) that it is their way of diversifying.
    Vollmer uses rituxan and Ocrevus interchangeably in his talks.
    Linda~~~~

    Be the kind of woman that when your feet hit the floor each morning the devil says:"Oh Crap, She's up!"

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    Quote Originally Posted by stillstANNding View Post
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    Does it seem like Genentech wants us to take Ocrevus instead of Rituxan? If so, why?

    ANN
    Money money money money.
    Linda~~~~

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    Distinguished Community Member SuzE-Q's Avatar
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    Quote Originally Posted by stillstANNding View Post
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    Does it seem like Genentech wants us to take Ocrevus instead of Rituxan? If so, why?

    ANN
    Think the patent just ended on Rituxan, so cheaper generics will be available. And so they rebranded and marketed as Ocrevus to try and keep the cash cow coming in.
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