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Thread: Debate on rituximab vs. ocrelizumab (Rituxan vs. Ocrevus) in MS Journal

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    Distinguished Community Member agate's Avatar
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    Default Debate on rituximab vs. ocrelizumab (Rituxan vs. Ocrevus) in MS Journal

    I'm not sure that these articles tell anything not already covered here but just in case anyone is interested, the Multiple Sclerosis Journal has published an article in favor of Rituxan as an acceptable alternative to Ocrevus in treating MS, another article opposed, and a commentary on both articles:

    http://journals.sagepub.com/doi/full...52458518757930 (Yes)

    http://journals.sagepub.com/doi/full...52458518757931 (No)


    http://journals.sagepub.com/doi/full...52458518760717 (Commentary)
    MS diagnosed 1980. Avonex 2002-2005. Copaxone 6/07 - 5/10.
    Member of this MS board since 2001.

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    Distinguished Community Member Sunshine's Avatar
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    These are very interesting articles.

    A nurse at my infusion center said Rituxan is more expensive than Ocrevus. But this article says the opposite.

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    Quote Originally Posted by Sunshine View Post
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    These are very interesting articles.

    A nurse at my infusion center said Rituxan is more expensive than Ocrevus. But this article says the opposite.
    This article is correct. Don’t you remember...the patent on rituximab was running out so the company tweaked it, changed the name to Ocrevus, and kept the price high on Ocrevus. Follow the money. It always leads to the truth.
    Linda~~~~

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    Ocrevus is nearly a third more per dose than rituxan. Made by the same company...Genentech.

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    Distinguished Community Member Sunshine's Avatar
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    Thanks. I guess the RN was misinformed

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    Does it seem like Genentech wants us to take Ocrevus instead of Rituxan? If so, why?

    ANN
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    Quote Originally Posted by stillstANNding View Post
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    Does it seem like Genentech wants us to take Ocrevus instead of Rituxan? If so, why?

    ANN
    Money money money money.
    Linda~~~~

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    Quote Originally Posted by stillstANNding View Post
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    Does it seem like Genentech wants us to take Ocrevus instead of Rituxan? If so, why?

    ANN
    Think the patent just ended on Rituxan, so cheaper generics will be available. And so they rebranded and marketed as Ocrevus to try and keep the cash cow coming in.
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    Why do they do Rituxon two weeks apart. Is it a half dose like the Ocrevus first time?
    Be the person your dog thinks you are

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    Quote Originally Posted by ssusan View Post
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    Why do they do Rituxon two weeks apart. Is it a half dose like the Ocrevus first time?
    What is the Ocrevus dose? Then what is the rituxan dose? Do they determine dose by the patient’s weight so that we all get different doses?
    I have never heard the words about half dose applied to any of my rituxan infusions. I just know that it is the standard protocol that is used for rituxan infusions for all my friends on rituxan here or at the MS clinic where Ionete is. Good question for her!
    Linda~~~~

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