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Thread: Ublituximab looks good

  1. #1
    Distinguished Community Member Sunshine's Avatar
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    Default Ublituximab looks good

    https://www.medscape.com/viewarticle...=1552978&faf=1

    I wonder what itís PR name will be? Ubliterate?name that drug!

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  3. #2
    Distinguished Community Member agate's Avatar
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    Utuxin may be one of its names:

    http://adisinsight.springer.com/drugs/800031892

    I like "Ubliterate." You obliterate MS?
    MS diagnosed 1980. Avonex 2002-2005. Copaxone 6/07 - 5/10.
    Member of this MS board since 2001.

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  5. #3
    Distinguished Community Member Frog42's Avatar
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    Maybe Tux, like you're dressed up to go somewhere important.


    Whatever happens around you, don't take it personally. Nothing other people do is because of you. It is because of themselves. -- Miguel Ruiz

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    Distinguished Community Member Lazarus's Avatar
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    What is this site? Anyway, the iMac at the end means it is a monoclonal antibody? Rituximab and Ocrevus have the same ending. Ocrevus and rituxan areused for non Hodgkins lymphoma too....and myesthenia gravis (sp)....
    Linda~~~~

    Be the kind of woman that when your feet hit the floor each morning the devil says:"Oh Crap, She's up!"

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  9. #5
    Distinguished Community Member agate's Avatar
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    Yes, the -mab ending on a drug indicates that it's a monoclonal antibody.

    This guide to drug names is long but might be of some use:

    https://druginfo.nlm.nih.gov/m.drugp...nericStems.jsp
    MS diagnosed 1980. Avonex 2002-2005. Copaxone 6/07 - 5/10.
    Member of this MS board since 2001.

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  11. #6
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    The more the merrier! Doesn't depleting B cells sometimes cause infections?
    Virginia

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  13. #7
    Distinguished Community Member agate's Avatar
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    Quote Originally Posted by Virginia View Post
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    The more the merrier! Doesn't depleting B cells sometimes cause infections?
    This seems to have been a concern, at least with Rituxan. They're talking mainly about rheumatoid arthritis here but it looks as if patients were found to be more vulnerable to infection after their first infusions but otherwise the researchers found that Rituxan had a good safety profile:

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392126/
    MS diagnosed 1980. Avonex 2002-2005. Copaxone 6/07 - 5/10.
    Member of this MS board since 2001.

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    Distinguished Community Member Lazarus's Avatar
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    Quote Originally Posted by agate View Post
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    This seems to have been a concern, at least with Rituxan. They're talking mainly about rheumatoid arthritis here but it looks as if patients were found to be more vulnerable to infection after their first infusions but otherwise the researchers found that Rituxan had a good safety profile:

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392126/
    Rituxan and Ocrevus have great safety records...almost no side effects (people take the infusions easily with no down time at all) and there is some evidence of repair. Limited repair but real. That’s why they are talked about as game changers.
    Linda~~~~

    Be the kind of woman that when your feet hit the floor each morning the devil says:"Oh Crap, She's up!"


  16. #9
    Distinguished Community Member Sunshine's Avatar
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    Which is why my immunologist rec against Rituxan due to my CVID , Immune Deficiency Syndrome.

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  18. #10
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    Mine recommended against Ocrevus due to age and immune system is not as good as we age.
    Virginia

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