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Thread: Demyelination..interesting prospect? Article from an MS Foundation site...

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    Distinguished Community Member Lazarus's Avatar
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    Default Demyelination..interesting prospect? Article from an MS Foundation site...

    Scientists find novel cell type linked to myelination
    January 18, 2018
    Researchers at the University of Göttingen's Institute of Neuropathology report discovering a novel oligodendroglial cell type. The cell type appears only when a myelin sheath is being created. They hope the cells will help to identify new regenerative drugs.

    A crucial prerequisite for the development of therapies that promote repair is a better understanding of myelin formation. Oligodendrocytes are specialized glial cells that are responsible for myelination in the central nervous system. The team believes that the BCAS1-positive oligodendrocytes they discovered represent an intermediate stage in the development of myelin-forming cells.

    In humans they can only be identified for a relatively short period of time, exactly then when myelin is actually being formed. In the human brain, for example, they are found in newborns, which generate myelin at high rate. In adults, these cells disappear, but they can be re-formed when myelin has been damaged and needs to be regenerated.

    Results of mouse model studies sometimes do not translate to humans and may be years away from being a marketable treatment. The researchers hope that the BCAS1 positive cells will help to identify new regenerative medicines. According to the researchers, we can now rapidly screen for drugs that promote the formation of these cells. Furthermore they could be used to get a better understanding of exactly when and how myelin is created during the course of a human life.

    The findings were published in the journal Science Translational Medicine.
    Linda~~~~

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    Distinguished Community Member Sunshine's Avatar
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    Interesting research. We may be the last generation of MS patients that die uncured. Future MS patients, about 30 years from now, will be cured.

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    Distinguished Community Member Lazarus's Avatar
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    Quote Originally Posted by Sunshine View Post
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    Interesting research. We may be the last generation of MS patients that die uncured. Future MS patients, about 30 years from now, will be cured.
    That’s what I think....there has been so much progress in my own 27 year journey....the next MSgeneration will be that much luckier again to live when there is a cure..
    Linda~~~~

    Be the kind of woman that when your feet hit the floor each morning the devil says:"Oh Crap, She's up!"

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    Distinguished Community Member Howie's Avatar
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    A true cure has to cover two aspects of this disease. Stop the body from attacking the nervous system entirely, and to repair the damage that has already been done. Progress on both aspects is being made, but it is slow, and too slow to do me any good. But for people in the future, it may usher in the end of MS.

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    Distinguished Community Member Lazarus's Avatar
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    Yesterday on the news I listened to a story about Bill Gates and the Gates Foundation. They are putting billions into setting up an attack on Alzheimer’s disease. This is brain research which, I believe, has tentacles that spread to lots of brain disorders. It is a very good thing. A well funded research focus on the brain.
    Linda~~~~

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    Distinguished Community Member Sunshine's Avatar
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    What good people to spend their fortune on health initiatives

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