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Thread: Vitamin D in Optic Neuritis Recovery

  1. #1
    Distinguished Community Member SuzE-Q's Avatar
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    Default Vitamin D in Optic Neuritis Recovery

    Mult Scler. 2016 Apr 1. pii: 1352458516642315. [Epub ahead of print]

    A prospective cohort study of vitamin D in optic neuritis recovery.

    Burton JM1, Eliasziw M2, Trufyn J3, Tung C4, Carter G5, Costello

    Abstract
    BACKGROUND:
    Vitamin D sufficiency is associated with better inflammatory outcomes in multiple sclerosis (MS). We hypothesize that it is also associated with better long-term neurodegenerative measures.

    OBJECTIVES:
    To show that vitamin D sufficient patients (25-hydroxy vitamin D (25(OH)D) > 80 nmol/L) have better optical coherence tomography (OCT) neuroaxonal measures of ganglion cell layer (GCL) and retinal nerve fiber layer (RNFL) thickness after optic neuritis.

    METHODS:
    In this prospective cohort study, acute optic neuritis patients underwent OCT and serum 25(OH)D assessments at baseline and at month 6, with comparisons between vitamin D sufficient and insufficient patients, and men and women. Potential confounding variables were evaluated.

    RESULTS:
    Of 49 enrolled, 36 had complete, analyzable data. At baseline, vitamin D insufficiency was associated with greater RNFL thickness (134.3 vs. 95.2 Ám; p = 0.003) in affected eyes. At month 6, insufficient patients had greater GCL thinning (GCL inter-eye difference: 14.2 vs. 4.0 Ám, p = 0.008). Men had greater RNFL and GCL thinning than women (GCL: 61.2 vs. 69.6 Ám, p = 0.036).

    CONCLUSION:
    Acutely, in optic neuritis, RNFL thickness is increased with vitamin D insufficiency. Chronically, neuronal, and possibly axonal loss are associated with vitamin D insufficiency and male gender, suggesting vitamin D and female gender may confer neuroprotection in optic neuritis, and possibly, central nervous system (CNS) inflammatory disease
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  3. #2
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    I wonder if this had any thing to do with my getting over my optic neuritis as well as I did when I had It?
    Virginia

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    Good question Virginia! Me too.
    Love, Sally


    "The best way out is always through". Robert Frost







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  7. #4
    Distinguished Community Member SuzE-Q's Avatar
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    I think there's naturally a high recovery rate from ON.

    Wouldn't hurt to start swallowing some if our eyes start acting up though.

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    Distinguished Community Member Howie's Avatar
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    I take D and E daily, and have for awhile. I love doing something, and then research comes along to back it up!
    Evolution spans the Universe.

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    Distinguished Community Member Lazarus's Avatar
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    I remember that years ago I was taking large doses of vitamin D when I tested low...
    I remember that I was taking vitamin D3...does anyone know what that is as opposed to Vitamin D?
    Linda~~~~

    Be the kind of woman that when your feet hit the floor each morning the devil says:"Oh Crap, She's up!"

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  13. #7
    Distinguished Community Member agate's Avatar
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    Quote Originally Posted by Lazarus View Post
    This quote is hidden because you are ignoring this member. Show Quote
    I remember that years ago I was taking large doses of vitamin D when I tested low...
    I remember that I was taking vitamin D3...does anyone know what that is as opposed to Vitamin D?
    Vitamin D3 is the preferred form if you're taking a supplement. A prescription type is a different story apparently. D3 is cholecalciferol, vitamin D in a natural form, made by your body from sunlight. D2 is calciferol, from an irradiated fungus and not naturally made by the body.

    http://www.webmd.com/osteoporosis/fe...amin-d-is-best
    MS, diagnosed 1980. Avonex 2001-2004. Copaxone 2006-2009.

    "Always put off until tomorrow whatever you think you should do today." --Anonymous



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  15. #8
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    A while back my doc wrote me a script for vit D I don't remember which it was but seems like it was for 50,000 units (?) of course the ins didn't cover it and after 3 or 4 months I quit taking it as I didn't notice any difference. I do remember the blood work (which also the ins didn't cover) showed that I had nearly 0 in my system. I believe it was like $17.00 a month but added to all the other meds I take that I HAVE to take.....something has gotta give. Funny I found that Medicaid covers it but Medicare does not. Like cough meds and Valium, Xanax etc same deal Medicaid covers them but Medicare doesn't. No one has ever been able to explain why. Even the pharmacist just looked at me shrugged his shoulders and said he had no idea why it was the way it is.

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  17. #9
    Distinguished Community Member Howie's Avatar
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    D3 is also called Cholecalciferol, or at least that's what it says on the bottle.
    Evolution spans the Universe.

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    Howie, you are becoming so educated in your new putter life!
    Love, Sally


    "The best way out is always through". Robert Frost







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